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Lissencephaly Lissencephaly with cerebellar hypoplasia Lissencephaly (Miller-Dieker) or isolated lissencephaly X-linked lissencephaly with hypogonadism (Partington syndrome) Muscle-eye-brain disease Walker-Warburg Holoprosencephaly Double cortex Double cortex or X-linked lissencephaly Heterotopias Periventricular nodular heterotopia Tuberous sclerosis Tuberous sclerosis Fukuyama muscular dystrophy Schizencephaly Schizencephaly Microcephaly Microcephaly Microcephaly
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side chains have a charge at neutral pH and strongly prefer to be on the exterior, exposed to water, rather than in the interior of the protein. The terms acidic and basic for residues may seem a little strange. Asp and Glu are called acidic amino acids, although at neutral pH in most proteins, Asp and Glu are not present in the acidic form ( COOH) but are present in the basic form ( COO ). So the acidic amino acids, Asp and Glu, are really bases (proton acceptors). The reason that Asp and Glu are called acidic residues is that they are such strong acids (proton donors) they have already lost their protons. Lys, Arg, and His are considered basic amino acids, even though they have a proton at neutral pH. The same argument applies: Lys, Arg, and His are such good bases (proton acceptors) that they have already picked up a proton at neutral pH.
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we are focusing on these two signs as excellent mealtime starter signs. As babies near their first birthday, however, both their minds and their palates have progressed to the point that even more specific mealEat Milk time signs are needed. Not only do they know in general that they are hungry, they also know more specifically whether they are ready for their bib, would like something to drink or would rather have cereal to eat, want more of what they already have or, instead, are ready to get down from their chair because they are all done. Signs like these help ensure that mealtimes are happy times rather than occasions for tantrums and tears. And they work for snacktime, too. Are Goldfish crackers a mainstay of your More than Crackers All Gone baby s diet Use the cracker sign, or even Still chewing his first cracker, try the fish sign. We can t tell you how fourteen-month-old Austin toddled many times we ve seen babies calmly over to his mom and signed cracker asking for Goldfish crackers by using the followed by the all done sign. Oh, you want another cracker, said more and fish signs together. And when his mom as she gave him one. A there are no more left to give, the all done few minutes later Austin was back sign can convey the bad news. again. Instead of requesting a third In addition to these signs, the Baby cracker, however, Austin signed Signs dictionary also includes other signs spider. Looking down, his mom saw a spider on a collision course for specific foods: apple, banana, bread, carwith her foot. She was just about to rot, cheese, chicken, cookie, cracker, egg, fruit, say, That s right, that is a spider, grapes, hot dog, juice, orange, peas, and yogurt. when Austin smashed it with his Our research has also shown a number shoe, grinned up at her, and signed of nonfood signs to be especially releall done. There was no doubt about it the spider, like the cracker, was vant to mealtime: the hot sign can be useindeed all done! ful to let parents know when food is too
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MEIENBERG O: Sparing of the temporal crescent in homonymous hemianopia and its signi cance for visual orientation. Neuroophthalmology 2:129, 1981. MINCKLER DS, TSO MOM, ZIMMERMAN LE: A light microscopic autoradiographic study of axoplasmic transport in the optic nerve head during ocular hypotony, increased intraocular pressure, and papilledema. Am J Ophthalmol 82:741, 1976. NEWMAN NJ: Optic neuropathy. Neurology 46:315, 1996. PANDIT RJ, GALES K, GRIFFITHS PG: Effectiveness of testing of visual elds by confrontation. Lancet 358:1339, 2001. PEARLMAN AJ: Visual system, in Pearlman AL, Collins RC (eds): Neurobiology of Disease. New York, Oxford University Press, 1990, chap 7, pp 124 148. RIZZO JF, LESSELL S: Optic neuritis and ischemic optic neuropathy. Arch Ophthalmol 109:1668, 1999. RUCKER CW: Sheathing of retinal venus in multiple sclerosis. Mayo Clin Proc 47:335, 1972. SADUN RA, MARTONE JF, MUCI-MENDOZA R, et al: Epidemic optic neuropathy in Cuba: Eye ndings. Arch Ophthalmol 112:691, 1994. SAVINO PJ, PARIS M, SCHATZ NJ, et al: Optic tract syndrome. Arch Ophthalmol 96:656, 1978. SAWLE GV, JAMES CB, ROSS M, RUSSELL RW: The natural history of non-arteritic anterior ischemic optic neuropathy. J Neurol Neurosurg Psychiatry 53:830, 1990. SLAVIN M, GLASER JS: Acute severe irreversible visual loss with sphenoethmoiditis-posterior orbital cellulitis. Arch Ophthalmol 105:345, 1987. SMITH JL, HOYT WP, SUSAC JO: Optic fundus in acute Leber s optic atrophy. Arch Ophthalmol 90:349, 1973. THE CUBA NEUROPATHY FIELD INVESTIGATION TEAM: Epidemic optic neuropathy in Cuba Clinical characteristics and risk factors. N Engl J Med 333:1176, 1995. TSO MOM, HAYREH SS: Optic disc edema in raised intracranial pressure: III. A pathologic study of experimental papilledema. Arch Ophthalmol 95:1448, 1977; IV: Axoplasmic transport in experimental papilledema, Arch Ophthalmol 95:1458, 1977. WEISKRANTZ L, WARRINGTON EK, SANDERS MD, MARSHALL J: Visual capacity in the hemianopic eld following a restricted occipital ablation. Brain 97:709, 1974. WRAY SH: Neuro-ophthalmologic diseases, in Rosenberg RN (ed): Comprehensive Neurology. New York, Raven Press, 1991, chap 20. WRAY SH: Visual aspects of extracranial carotid artery disease, in Bernstein EF (ed): Amaurosis Fugax. New York, Springer-Verlag, 1988, pp 72 80. YOUNG LHY, APPEN RE: Ischemic oculopathy. Arch Neurol 38:358, 1981.
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494 PART 3
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If x   32 32 ; the price for each stereo will be P 80 5 $26:67: 3 3
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A variant of the move-mailbox method is the swing method: 1. Install Exchange 2000 on a brand new machine running Windows 2000. 2. Join the new Exchange 2000 server to the existing Exchange 5.5 site. 3. Move mailboxes and public folders from the existing Exchange 5.5 site to the new Exchange 2000 server. 4. Delete Exchange 5.5 from the servers, upgrade their hardware, install Windows 2000 and then Exchange 2000 on them, and return to step 2 to upgrade all the sites. The advantages and disadvantages of this method are fairly obvious, given the previous discussion of the other two methods.
Part 9: Solid Modeling
De ne the auxiliary state composed of the accelerometer scale factor and misalignment matrix parameters to be xAa = [SFu , SFv , SFw , auw , auv , avw , avu , awv , awu ]. The partial derivative of fu f p = 0 xAa 0 f p with respect to xAa is 0 fv 0 0 0 fw fv 0 0 fw 0 0 0 fu 0 0 fw 0 0 0 fu 0 0 fv (11.121)
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