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var input = document.getElementById('DisplayUntil'); input.value = year + '-' + padZero(month, 2) + '-' + padZero(day, 2); } </script>
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15. We ll now add a small amount of code to the host application simply to tell us when each workflow completes. Insert the following code in the event handler for WorkflowCompleted:
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Figure 19-6. Check the wireless connection s General tab for possible connection problems.
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1. If the source code is not visible, just click the tab at the top of the code editor where you see the filename Form1.cs. Add a new line in the Button1_Click event, type MessageBox.Show, and then type (. The IntelliSense window opens and shows there are 21 possible variations for MessageBox.Show. 2. Scroll through the list of options using the up or down arrow on your keyboard. Once you find the one you want to use, simply use the code constructs as IntelliSense indicates to you. In this case, that means using the option identified as 1 of 21 in the yellow rectangle, which is called a tooltip. 3. Complete the following line of code so that it looks like this:
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Zend Framework: A Beginner s Guide
Information Management
Call Agent Call agents, sometimes called media gateway controllers, pro-
In this part: 23: Connecting Clients to Windows Networks. . . . . . . . . . . . . . 901 24: Configuring IP Addressing and Name Resolution. . . . . . . . 943 25: Connecting Remote Offices . . . . . . . . . . . . . . . . . . . . . . . . . . 995 26: Configuring Telephony and Conferencing . . . . . . . . . . . . . 1053
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There are cases when it is necessary to stop executing the statements in the loop for this iteration and go to the next iteration. VHDL includes a construct that accomplishes this. The NEXT statement allows the designer to stop processing this iteration and skip to the successor. When the NEXT statement is executed, processing of the model stops at the current point and is transferred to the beginning of the LOOP statement. Execution begins with the first statement in the loop, but the loop variable is incremented to the next iteration value. If the iteration limit has been reached, processing stops. If not, execution continues. Following is an example showing this behavior:
from the lumen and then allows potassium to enter the interstitium across the basolateral membrane via potassium channels. Regulation of potassium excretion involves multiple controls over the secretory processes in the distal nephron, something like a passenger van where everyone in it has an accelerator and a brake pedal. As is the case with regulation of sodium excretion, we cannot predict just how these controls operate in every situation. Fortunately, with potassium as well as sodium, the healthy kidneys do a remarkable job of doing the right thing, ie, increasing potassium excretion in response to high dietary loads and reducing excretion in the face of restricted diets. Even with experimental manipulations, it is hard to get healthy kidneys to do otherwise (but as described later, certain pathologies interfere with normal potassium regulation). Much of the regulation involves controlling the activity of potassium channels. The kidneys and other body organs express numerous potassium channel species; for simplicity, we do not usually differentiate between types. (Otherwise, we would have a whole book devoted entirely to potassium channels!) However in principal cells of the distal nephron two types of channels stand out as being those that secrete potassium in a regulated manner: ROMK (standing for renal outer medulla, because that is where they were first indentified) and BK (as each channel has a big capacity to secrete potassium). Owing to different combinations of channel subunits and alternative splicing of transcripts, several isoforms of each type of channel exist. Although ROMK and BK channels both conduct potassium, they play different roles and are regulated by quite different mechanisms.5 At very low dietary loads of potassium, there is virtually no secretion by either kind of channel. ROMK channels are sequestered in intracellular vesicles and BK channels are closed. At normal potassium loads, ROMK channels are moved to the luminal membrane and secrete potassium. BK channels are still closed, held in reserve and ready to respond to appropriate signals when needed. At high excretion rates, both types of channel are present in the luminal membrane and avidly secreting potassium (Figure 8 3). Figure 8 4 shows factors known to influence the secretion, and thus the ultimate excretion of potassium. The following text provides a brief description of how specific factors affect potassium excretion. (1) Plasma potassium. The role of plasma potassium is the most understandable influence. First, the filtered load is directly proportional to plasma concentration. Second, the environment of the principal cells, ie, the cortical interstitium, has a potassium concentration that is nearly the same as in plasma. The Na-K-ATPase that takes up potassium is highly sensitive to the potassium concentration in this space, and varies its pump rate up and down when potassium levels in the plasma vary up and down. Thus, plasma potassium concentration does exert an influence on potas5 BK channels require either an elevation in intracellular calcium or a large membrane depolarization in order to open them. ROMK channels are regulated by a multitude of intracellular signaling cascades. Some affect expression of the channels, some move channels back and forth between the luminal membrane and storage vesicles, while others alter the probability that the channel is in an open configuration. Although progress is being made in sorting out the details of these intracellular cascades, it is still a challenge to relate them to extrarenal signals that turn them on and off.
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